Question 1-3 of 7: Golgi Bodies (Structural Organization and Function of Intracellular Organelles) | SWAYAM Cell Biology | Includes PYQs | Get Solutions with Detailed Explanations

An investigator expresses a GFP-fused protein that localizes to the outer membrane of Golgi apparatus. Upon visualizing GFP-signal in the fluorescent microscope, it was noted that GFP is pericentrosomal in its localization (Fig A). Treatment of such GFP expressing cells with a newly identified drug disrupted the Golgi into small vesicles (Fig B)

Following is a list of potential targets of the drug:

1. Dynein complex

2. Myosin

3. Microtubules

4. Dicer

Choose the combination with all the correct targets:

Fluorescently tagged protein was used to study protein secretion in yeast. Fluorescence was observed in:

(1) The Golgi

(2) The secretory vesicles

(3) The rough ER

Which of the following describes the best sequence in which these events occur? (December)

A protein found in the Golgi compartment was found to be degraded rapidly at mitosis. Golgi extracts were treated by glycosidase and western blots done using antibodies against the protein. The following pattern was obtained.

Identify the statement that cannot be made based on the data.