Pedigree; Guidelines for Pedigree Analysis

Pedigree

A pedigree is a genealogical table, chart, or diagram that represents the ancestral line of an individual man or animal with a long lifespan and limited reproductive capabilities. Pedigrees are often passed down through families for generations. When adequate information about a family is available, the process of determining the precise way in which a gene is passed down across generations is known as pedigree analysis.

It is possible t…

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Capping: The Capping 5՚ Cap is Added to the Nascent RNA After the Initiation of Polymerase II

Capping

• In eukaryotes initial primary transcript synthesized by RNA polymerase II turn into a functional mRNA. In the before that the primary RNA contain the copy of exon and introns.
• There they are spliced and chemically modified in the nucleus before being transported in to nucleus. The development of a functional mRNA there are 3 major events occur during the process. They are;
  • 5 ′ capping,
  • 3 ′ clevage/polyadenylation
  • RNA splicing.
• The overlapping in protein that involved el…

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